REX/Osprey’s 21 Altcoin ETF Filings: What Investors Need to Know About the Next Wave of Crypto ETFs

The landscape for U. S. crypto ETFs is on the verge of a dramatic shift. On October 4,2025, REX Shares and Osprey Funds jointly filed applications with the SEC for 21 single-asset altcoin ETFs. This marks the largest multi-crypto ETF filing in U. S. history, and if approved, it will significantly expand regulated access to digital assets beyond Bitcoin and Ethereum.

These filings are not just about quantity. The REX/Osprey altcoin ETF list covers a wide spectrum of blockchain projects - from established Layer 1 protocols to next-gen DeFi infrastructure. Investors who have been waiting for institutional-grade vehicles to access tokens like Cardano (ADA), Solana (SOL), Avalanche (AVAX), and Polkadot (DOT) may soon have their opportunity.

What Makes the REX/Osprey Altcoin ETFs Unique?

The proposed lineup isn’t a generic basket fund or index tracker. Each ETF is structured as a single-asset trust, giving investors direct exposure to individual tokens. Here’s the full roster:

The 21 REX/Osprey Altcoin ETF Filings (October 2025)

1. 

   REX/Osprey Ethereum Trust ETF (ETH): Offers exposure to Ethereum, the leading smart contract platform and second-largest cryptocurrency by market cap. Includes potential staking rewards for ETH holders.
2. 

   REX/Osprey Solana Trust ETF (SOL): Tracks Solana, known for its high throughput and low fees. This ETF targets investors seeking access to a fast-growing Layer 1 blockchain.
3. 

   REX/Osprey Ripple (XRP) Trust ETF: Provides regulated access to XRP, a token focused on cross-border payments and institutional adoption. Ripple’s legal clarity may boost investor confidence.
4. 

   REX/Osprey Cardano Trust ETF (ADA): Focuses on Cardano, a proof-of-stake blockchain with a strong academic foundation. Staking integration allows investors to earn ADA rewards.
5. 

   REX/Osprey Avalanche Trust ETF (AVAX): Targets Avalanche, a highly scalable Layer 1 platform. Staking features offer the potential for additional AVAX yield.
6. 

   REX/Osprey Polygon Trust ETF (MATIC): Offers exposure to Polygon, a leading Ethereum scaling solution, supporting DeFi and NFT ecosystems.
7. 

   REX/Osprey Polkadot Trust ETF (DOT): Tracks Polkadot, a multichain network enabling interoperability between blockchains. Includes staking rewards for DOT holders.
8. 

   REX/Osprey Chainlink Trust ETF (LINK): Provides access to Chainlink, the top decentralized oracle network powering smart contract data feeds.
9. 

   REX/Osprey Litecoin Trust ETF (LTC): Follows Litecoin, a long-standing cryptocurrency known for fast, low-cost transactions and a strong security record.
10. 

    REX/Osprey Stellar Lumens Trust ETF (XLM): Focuses on Stellar Lumens, designed for cross-border payments and financial inclusion.
11. 

    REX/Osprey Uniswap Trust ETF (UNI): Tracks Uniswap, the largest decentralized exchange protocol by trading volume, central to DeFi innovation.
12. 

    REX/Osprey Cosmos Trust ETF (ATOM): Offers exposure to Cosmos, a network of interoperable blockchains. ATOM staking may provide additional yield.
13. 

    REX/Osprey Internet Computer Trust ETF (ICP): Follows Internet Computer, a protocol aiming to decentralize cloud computing and web services.
14. 

    REX/Osprey Arbitrum Trust ETF (ARB): Provides access to Arbitrum, a leading Layer 2 scaling solution for Ethereum, enabling faster and cheaper transactions.
15. 

    REX/Osprey Aptos Trust ETF (APT): Tracks Aptos, a high-performance Layer 1 blockchain focused on scalability and security.
16. 

    REX/Osprey Near Protocol Trust ETF (NEAR): Offers exposure to NEAR Protocol, a sharded, developer-friendly blockchain with staking capabilities.
17. 

    REX/Osprey Optimism Trust ETF (OP): Follows Optimism, an Ethereum Layer 2 solution leveraging optimistic rollups to scale decentralized applications.
18. 

    REX/Osprey Hedera Hashgraph Trust ETF (HBAR): Tracks Hedera Hashgraph, a public distributed ledger focused on enterprise-grade performance and security.
19. 

    REX/Osprey Algorand Trust ETF (ALGO): Provides access to Algorand, a proof-of-stake blockchain designed for speed, security, and decentralization.
20. 

    REX/Osprey Fantom Trust ETF (FTM): Focuses on Fantom, a fast, scalable Layer 1 platform supporting DeFi and enterprise use cases.
21. 

    REX/Osprey The Graph Trust ETF (GRT): Offers exposure to The Graph, a decentralized indexing protocol powering blockchain data queries.

This includes:

• REX/Osprey Ethereum Trust ETF (ETH)
• REX/Osprey Solana Trust ETF (SOL)
• REX/Osprey Ripple Trust ETF (XRP)
• REX/Osprey Cardano Trust ETF (ADA)
• REX/Osprey Avalanche Trust ETF (AVAX)
• REX/Osprey Polygon Trust ETF (MATIC)
• REX/Osprey Polkadot Trust ETF (DOT)
• REX/Osprey Chainlink Trust ETF (LINK)
• REX/Osprey Litecoin Trust ETF (LTC)
• REX/Osprey Stellar Lumens Trust ETF (XLM)
• REX/Osprey Uniswap Trust ETF (UNI)
• REX/Osprey Cosmos Trust ETF (ATOM)
• REX/Osprey Internet Computer Trust ETF (ICP)
• REX/Osprey Arbitrum Trust ETF (ARB)
• REX/Osprey Aptos Trust ETF (APT)
• REX/Osprey Near Protocol Trust ETF (NEAR)
• REX/Osprey Optimism Trust ETF (OP)
• REX/Osprey Hedera Hashgraph Trust ETF (HBAR)
• REX/Osprey Algorand Trust ETF (ALGO)
• REX/Osprey Fantom Trust ETF (FTM)
• REX/Osprey The Graph Trust ETF (GRT)

This breadth means investors could soon get regulated exposure to everything from Layer 1s like NEAR and ICP to DeFi blue chips such as Uniswap and Chainlink - all without direct token custody risk.

The Staking Advantage: More Than Just Price Exposure

A critical differentiator in these filings is staking integration. Several ETFs in this batch - specifically those tracking ADA, AVAX, DOT, NEAR, SUI, TAO, SEI, HYPE - are designed to participate directly in proof-of-stake networks. For investors, this means potential yields from both price appreciation and on-chain staking rewards.

This dual-yield structure could be a game changer for portfolio construction. It also introduces new complexities around tax treatment and operational risk that traditional equity or commodity ETFs don’t face. The funds plan to use Cayman Islands subsidiaries to navigate U. S. regulatory requirements while preserving staking eligibility - an approach already used by some commodity trusts but still untested at this scale in crypto.

Navigating Regulatory Uncertainty: Approval Timelines Remain Murky

The SEC’s recent adoption of generic listing standards was supposed to streamline crypto commodity-based products. However, ongoing government shutdowns have created approval backlogs across all digital asset filings - including these new altcoin ETFs.

No timeline for approval has been confirmed as of November 2025. Investors should expect delays and continued regulatory scrutiny around both spot market manipulation risks and staking mechanics within an exchange-traded wrapper.

For those seeking diversified crypto exposure, the REX/Osprey filings are a double-edged sword. On one hand, the ability to access single-asset altcoin ETFs like REX/Osprey Polygon Trust ETF (MATIC), REX/Osprey Chainlink Trust ETF (LINK), or REX/Osprey Uniswap Trust ETF (UNI) through a regulated brokerage account is a significant step forward. It removes many of the operational headaches and custody risks that have historically limited institutional and retail adoption.

On the other hand, these products are not without serious risk. Underlying token volatility remains extreme, altcoins like Fantom (FTM), Algorand (ALGO), or The Graph (GRT) can experience double-digit swings in a single session. Add in staking rewards with their own technical and regulatory uncertainties, and you have a complex risk profile that demands careful position sizing and ongoing monitoring.

Comparing the 21 REX/Osprey Altcoin ETFs: Which Tokens Stand Out?

The breadth of this ETF roster is unprecedented for U. S. markets. Here’s how some of the most prominent filings compare across major categories:

Layer 1 Protocols: Ethereum (ETH), Solana (SOL), Cardano (ADA), Avalanche (AVAX), Polkadot (DOT), Near Protocol (NEAR), Internet Computer (ICP), Aptos (APT), Algorand (ALGO), Fantom (FTM)

Layer 2 and Scaling: Polygon (MATIC), Arbitrum (ARB), Optimism (OP)

DeFi and Infrastructure: Uniswap (UNI), Chainlink (LINK), The Graph (GRT)

Payments and Interoperability: Ripple/XRP, Stellar Lumens (XLM), Cosmos/ATOM, Hedera Hashgraph (HBAR)

This diversity means investors can tailor exposure to specific narratives or ecosystems without taking on broad index risk. However, it also requires understanding each protocol’s unique fundamentals, from network security models to governance structures, before allocating capital.

Pragmatic Considerations Before Investing

If approved, these ETFs will likely see strong inflows from both retail and institutional channels hungry for compliant altcoin access. But early adopters should remain clear-eyed about potential pitfalls:

• Liquidity Risk: Some tokens in this list, such as ICP or GRT, have far lower trading volumes than majors like ETH or SOL. ETF liquidity could be challenged during periods of market stress.
• Tracking Error: Single-asset crypto ETFs must manage custody, slippage, staking logistics, and foreign product exposure. This introduces tracking error relative to spot token prices.
• Regulatory Overhang: Any adverse SEC decision or new guidance on staking could delay launches or force structural changes midstream.
• Custody and Counterparty Risk: Even with regulated wrappers, investors are still exposed to third-party custodians and offshore subsidiaries, points of failure not present in direct token ownership.

What Comes Next?Monitoring Approval and Market Impact

The next wave of U. S. -listed crypto ETFs will hinge on how regulators address these filings. If greenlit, expect rapid expansion into staking-enabled products and more diverse asset coverage from other issuers chasing first-mover advantage.

The bottom line: The REX Osprey crypto ETF filings represent a pivotal moment for multi-asset crypto investing in America. For those who plan their trades and protect their capital, these products could offer streamlined access to high-conviction narratives across protocols like Cardano, Solana, Avalanche, Polkadot, Chainlink, Uniswap, and more.
If you’re considering exposure via these new altcoin ETFs in 2025-2026, diligence is non-negotiable. Scrutinize each fund’s structure, risk disclosures, underlying liquidity profile, and remember that regulated doesn’t mean risk-free.